The Sydney Children's Hospitals Network's Pharmacy service works closely with health care teams to provide the best possible treatment options for patients. They stock a range of medicines and also specially develop medicines to suit individual patient needs. They are also heavily involved in clinical trials and invest considerable time in educating and training staff to support the quality use of medicines.

The Pharmacy service at The Children's Hospital at Westmead is a dedicated paediatric service.

The Sydney Children's Hospital, Randwick paediatric pharmacy operates as a component of the shared services agreement between the Network and Prince of Wales Hospital.