Levetiracetam information sheet

Contact details

Pharmacy, The Children’s Hospital at Westmead

Telephone: (02) 7825 2711

Introduction

Levetiracetam is an anti convulsant used to control seizures/fits. It can be used for focal, generalised and myoclonic seizure disorders. 

Medication instructions

How to give Levetiracetam

Levetiracetam must be prescribed by a doctor. You should never give your child anyone else's medications. 

Levetiracetam has very few drug interactions.  Your doctor will check and make sure that other drugs your child is taking are compatible with Levetiracetam.  This is also important if you are giving your child herbal or complementary medicines. The doctor can check to make sure they are compatible. 

Monitoring and medication levels 

Vitamin D may be affected by Levetiracetam so occasional blood tests may be performed. If you have any questions please ask your doctor. 

What to do if your child vomits

  • If your child vomits within 30 minutes after having their dose, then repeat the dose.
  • If it is longer than 30 minutes since having the dose you do not need to repeat the dose, but if vomiting or diarrhoea continues, seek medical help.

What to do if your child misses a dose

  • If a dose is missed, it should be taken as soon as it is remembered.
  • The next due dose should be taken at the usual time.
  • However, if the missed dose is remembered in close proximity to the next due dose (i.e. within 3 to 4 hours of the next dose), please seek medical advice.
  • If unsure about what to do, the treating GP, epilepsy nurse, paediatrician or neurologist should be contacted.

Medication storage and safety

Storage

Always follow the instructions of your doctor and pharmacist. 

See more about how to store different brands of Levetiracetam

 

Side effects

All medications have side effects. Not everyone will experience side effects. Levetiracetam has a good side effect profile with very few drug interactions. Below are some of the possible side effects your child may experience: 

Common Side Effects 

  • Drowsiness 

  • Behaviour or mood changes: e.g. anxiety, agitation, oppositional behaviour 

  • Aggression can occur and lead to cessation of drug 

  • Ataxia (unsteady walking) 

  • Dizziness 

Rare Side Effects 

  • Rash 

  • Blood disorders 

  • Liver dysfunction 

  • Suicidal ideation 

  • Psychosis 

Pregnancy and contraception 

Levetiracetam has a lower risk of malformations compared to other antiepileptic drugs. If a pregnancy is planned a discussion with your neurologist is recommended. 

For further information, refer to the reproductive health section.

The information provided in this resource is limited and does not replace the need for a medical consultation. It is very important you speak to your doctor about all aspects of your medication including side effects when medication is first prescribed. Report any concerns to your doctor promptly. 

Medication scripts

Please ask your child’s doctor at a follow up appointment for another medication script if required.

If this is a regular medicine for your child, the GP should be your first point of call for repeat prescriptions. 
 

Overdose information

In the case of an overdose or poisoning, call the NSW Poisons Information Centre on 13 11 26 (24 hour service).