Liver biopsy factsheet

Introduction

A liver biopsy is a test to check if your child has liver disease or damage. It also helps find the cause of the problem.

A biopsy means taking a small piece of tissue from the body to test it. A specialist doctor, called a pathologist, checks the sample.

 Before the procedure

Your child’s treatment team will explain:

  • when and where to come for the procedure
  • if and when your child needs to stop eating or drinking
  • if any blood tests are needed before the procedure.

An ultrasound may be used to mark where the biopsy will be done.

Your child will be given anaesthetic before the procedure to stop pain and make them sleepy. The doctor will tell you which type of anaesthetic will be used.

 During the procedure

Generally, in a liver biopsy:

  1. a small tube called an intravenous (IV) cannula is placed in your child’s arm
  2. anaesthetic is given through the IV cannula
  3. a small cut is made on the upper right side of your child’s belly
  4. a special needle is inserted through the cut and used to take a small piece of liver
  5. the sample is sent to a lab for testing
  6. your child will then slowly wake up from the procedure.

 After the procedure

After the biopsy, your child will wake up in the recovery area. A sandbag or pressure bandage will be placed on the site to help stop bleeding.

Your child will need to lie on their right side for up to 6 hours, or until their treatment team says they can safely move.

Most children stay in hospital overnight to make sure they recover well. If there are no problems, they can usually go home the next morning.

The dressing must stay in place for 24 hours. Let the nurse or doctor know if you have questions.

 Management

Complications and risks

It is normal to have some pain near the biopsy site or in the right shoulder. Pain medicine will be given as needed. Nurses and doctors will check your child often while in hospital.

Serious but rare risks include:

  • bleeding
  • infection
  • puncture of the lungs
  • damage to the gallbladder or bile tubes.

Speak to your child’s treatment team if you have any concerns.

Disclaimer

This factsheet is provided for general information only. It does not constitute health advice and should not be used to diagnose or treat any health condition.

Please consult with your doctor or other health professional to make sure this information is right for you and/or your child.

The Sydney Children’s Hospitals Network does not accept responsibility for inaccuracies or omissions, the interpretation of the information, or for success or appropriateness of any treatment described in the factsheet.

© Sydney Children’s Hospitals Network 2025


This factsheet was produced with support from John Hunter Children's Hospital.