White blood cell (WBC) scan factsheet
Introduction
A white blood cell (WBC) scan is an imaging test that helps find infection or inflammation in your child’s body.
The test shows doctors where white blood cells are travelling. This can help understand where there is swelling or inflammation and how your child’s immune system is responding.
It uses:
- a Gamma camera – a large camera that measures radiation
- radiotracer- a small amount of radioactive fluid that moves through the body
The gamma camera takes pictures of the radiotracer as it moves through your child’s body, helping doctors see where white blood cells are going.
A white blood cell scan can be done to diagnose or check conditions like:
- inflammatory bowel disease (IBD)- swelling or irritation of the bowel, the lower part of the digestive system
- crohn’s disease – an ongoing condition that causes inflammation in the lining of the intestines
- osteomyelitis- a bone infection caused by bacteria
- abscesses- infected or swollen areas that may be filled with pus
- pyrexia of unknown origin (PUO)- an ongoing fever with no clear cause
- other inflammatory conditions.
Before the scan
Your child can eat and drink normally before the scan. Your child will be weighed to help calculate the correct amount of radiotracer.
The risks of radiation and allergic reactions are very low. Let your child’s treatment team know if they have any allergies.
Numbing cream
Needles can be uncomfortable for children. Numbing cream can be used for children over two years old.
If your child needs numbing cream, you will need to:
- ask for it before the day of the scan
- arrive 30 minutes early to the appointment so it has time to work.
During the scan
Your child will not feel anything during the scan, and the camera will not touch them.
The scan takes about five hours and is completed in four parts.
You can stay with your child. You may need to briefly leave the room if your child needs the additional X-ray scan.
Generally, the steps of the scan are:
Part 1:
- a small amount of blood is taken with a small ‘butterfly’ needle
- if your child has a central line, this may be used instead
- the nuclear medicine team will mix the radiotracer with the blood
- you and your child will return to the department about 1.5 hours later for the next step.
Part 2:
- the blood mixed with radiotracer is gently injected back into your child using a butterfly needle
- if your child has a central line, this may be used instead
- you and your child will return to the department again about one hour later for imaging
Part 3:
- your child will lie on the scanning bed
- a blanket with velcro straps may be used to help keep your child still
- the camera will take pictures of your child’s neck and tummy for about 15 minutes
- you and your child will return to the department again about two hours later for imaging.
Part 4:
- your child will lie on the scanning bed
- a blanket with velcro straps may be used to help keep your child still
- the camera will take more detailed pictures of the tummy over about 45 minutes, moving around your child to get different views.
The nuclear medicine team will let you know if you need further scans.
SPECT-CT scan
Some children need extra scans, like a SPECT-CT (single-photon emission computed tomography with CT) scan.
In the SPECT-CT scan, a camera moves slowly in a circle around your child. It will take detailed images of the belly and the digestive system.
Sometimes, a CT scan using low-dose X-rays is also used to show the shape and structure of the organs.
These extra scans do not need another injection.
After the scan
You can leave once the images are checked by a doctor or nuclear medicine scientist.
The results will be sent to your child’s doctor within a couple of days. You will need to schedule a follow-up appointment with your child’s doctor to discuss the results.
Management
Radiation
Your child will be exposed to a small amount of radiation during the scan. The benefits of finding and treating infection are greater than the small risk of this low dose.
Allergic reactions
Allergic reactions to radiotracer are very rare and usually mild. Your child’s doctor will talk to you about any potential risks before the scan. Let your child’s treatment team know if they have any allergies.
Supporting your child during the scan
Scans can be stressful for children. You can help by:
- explaining why the test is needed and how it works in simple words
- bringing comfort items like a blanket, toy, or dummy
- reassuring your child that you will remain with them the entire time
- asking the treatment team about support from Child Life Therapy services
- arriving 30 minutes early if using numbing cream.