Clobazam information sheet

• Clobazam must be prescribed by a doctor. You should never give your child anyone else's medications
• If Clobazam is withdrawn it must be done slowly under medical supervision. Stopping Clobazam too quickly can cause seizures.
• There are some medications that are cannot be given together with Clobazam. So, always tell your doctor and pharmacist that your child is taking Clobazam.  
• Other medicines that also cause sedation may make your child too drowsy if given together with Clobazam. This is also important if you are giving your child herbal complementary or over-the-counter medicines.

Monitoring and medication levels 

There is no need to do regular blood monitoring with Clobazam. The only monitoring required is a seizure diary to see if there is a decrease in the number of seizures. 

• If your child vomits within 30 minutes after having their dose, then repeat the dose.
• If it is longer than 30 minutes since having the dose you do not need to repeat the dose, but if vomiting or diarrhoea continues, seek medical help.

• If a dose is missed, it should be taken as soon as it is remembered.
• The next due dose should be taken at the usual time.
• However, if the missed dose is remembered in close proximity to the next due dose (i.e. within 3 to 4 hours of the next dose), please seek medical advice.
• Contact your treating GP, epilepsy nurse, paediatrician or neurologist if you are unsure about what to do. 

• Always read the label. Follow the instructions of your doctor and pharmacist.
• Keep out of reach of children.

See more about how to store different brands of Clobazam 

All medications have side effects. Not everyone will experience side effects. Below are some of the possible side effects your child may experience: 

Sedation

• Sedation is a common side effect of Clobazam
• This usually improves 2-3 weeks after starting the medication – if drowsiness continues after this period, discuss it with your doctor
• Sometimes, Clobazam can cause too much drowsiness, especially in children with swallowing or movement problems. It may interfere with feeding, swallowing or rarely breathing – if this happens, seek help immediately.

Rash

• If your child develops a rash, there are important features to look for such as: your child may develop red eyes, red mouth, and/or blisters around the mouth, nose and lips.
• If your child develops any of these symptoms please seek help as soon as you can.
• The drug may need to be stopped immediately under medical supervision.

Irritability

• Some children can become more irritable than usual.
• They can have sudden aggressive outbursts, hyperactivity, insomnia (inability to sleep), or depression.
• These latter side effects are only seen occasionally.

Drooling

• Your child may develop an increase in saliva and have some drooling. If this occurs and is a concern, please let your doctor know.

Other possible side effects

• Constipation
• Loss of appetite
• Dizziness
• Unsteadiness
• Dry mouth
• Hyperexcitability

Pregnancy and contraception 

If a pregnancy is planned, a discussion with your neurologist is recommended. For further information, refer to the reproductive health section.

The information provided in this resource is limited and does not replace the need for a medical consultation. It is very important you speak to your doctor about all aspects of your medication including side effects when medication is first prescribed. Report any concerns to your doctor promptly.